BDBM50000857 2-(1-methoxy-1-(3-(naphthalen-2-ylmethoxy)phenyl)propyl)thiazole::2-{1-Methoxy-1-[3-(naphthalen-2-ylmethoxy)-phenyl]-propyl}-thiazole::CHEMBL423835::ICI-211965

SMILES CCC(OC)(c1nccs1)c1cccc(OCc2ccc3ccccc3c2)c1

InChI Key InChIKey=XYRDHZXSQUWVCD-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50000857   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50000857(2-{1-Methoxy-1-[3-(naphthalen-2-ylmethoxy)-phenyl]...)
Affinity DataIC50: 500nMAssay Description:Compound was tested for the inhibition of 5-lipoxygenase (5-Lpo) in rat whole blood.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50000857(2-{1-Methoxy-1-[3-(naphthalen-2-ylmethoxy)-phenyl]...)
Affinity DataIC50: 100nMAssay Description:Inhibition of 5-lipoxygenase in human whole blood.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50000857(2-{1-Methoxy-1-[3-(naphthalen-2-ylmethoxy)-phenyl]...)
Affinity DataIC50: 8nMAssay Description:Inhibition of 5-lipoxygenase in mouse macrophages.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50000857(2-{1-Methoxy-1-[3-(naphthalen-2-ylmethoxy)-phenyl]...)
Affinity DataIC50: 400nMAssay Description:Inhibition of 5-lipoxygenase in human whole blood.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50000857(2-{1-Methoxy-1-[3-(naphthalen-2-ylmethoxy)-phenyl]...)
Affinity DataIC50: 150nMAssay Description:In vitro potency against human 5-LipoxygenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50000857(2-{1-Methoxy-1-[3-(naphthalen-2-ylmethoxy)-phenyl]...)
Affinity DataIC50: 400nMAssay Description:Inhibition of 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50000857(2-{1-Methoxy-1-[3-(naphthalen-2-ylmethoxy)-phenyl]...)
Affinity DataIC50: 400nMAssay Description:In vitro inhibition of leukotriene B4 synthesis in human whole blood by inhibiting 5-lipoxygenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed