BDBM50083351 (+/-)-[2-(4-benzylpiperidino)-1-(4-hydroxyphenyl)-1-propanol]::-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phenol::4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phenol::4-[2-(4-Benzyl-piperidin-1-yl)-1-hydroxy-propyl]-phenol::CHEMBL305187::ChEMBL_104385::IFENPRODIL

SMILES C[C@@H](C(c1ccc(cc1)O)O)N2CCC(CC2)Cc3ccccc3

InChI Key InChIKey=UYNVMODNBIQBMV-UHFFFAOYSA-N

Data  34 KI  16 IC50  1 EC50

PDB links: 4 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 51 hits for monomerid = 50083351   

TargetReplicase polyprotein 1ab(2019-nCoV)
Center For Free-Electron Laser Science

LigandPNGBDBM50083351(4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phen...)
Affinity DataEC50:  3.93E+4nMAssay Description:Briefly, Vero E6 cells (ATCC CRL-1586) seeded at 3.5 × 104 cells/well in 96-well plates were inoculated with 50 μ l of serial tenfold dilutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2021
Entry Details Article

TargetGlutamate receptor ionotropic, NMDA 2A(Human)
Indian Institute of Technology (Banaras Hindu University)

Curated by ChEMBL
LigandPNGBDBM50083351(4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phen...)
Affinity DataIC50: 1.46E+5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Indian Institute of Technology (Banaras Hindu University)

Curated by ChEMBL
LigandPNGBDBM50083351(4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phen...)
Affinity DataIC50: 340nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Anhui University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50083351(4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phen...)
Affinity DataIC50: 128nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTranslocator protein(Rat)
China Jiliang University

Curated by ChEMBL
LigandPNGBDBM50083351(4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phen...)
Affinity DataIC50: 0.730nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Indian Institute of Technology (Banaras Hindu University)

Curated by ChEMBL
LigandPNGBDBM50083351(4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phen...)
Affinity DataIC50: 264nMAssay Description:Antagonist activity at GluN2B receptor (unknown origin) expressed in Xenopus oocytes coexpressing GluN1a at -70 mV holding potential in presence of (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50083351(4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phen...)
Affinity DataIC50: 340nMAssay Description:Antagonist activity against NR1/NR2B receptor expressed in xenopus oocytes assessed as inhibition of NMDA induced Ca2+ influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50083351(4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phen...)
Affinity DataIC50: 177nMAssay Description:Antagonist activity against NR1a/NR2B receptor transfected in human HEK293 cells assessed as inhibition of NMDA-induced Ca2+ influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50083351(4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phen...)
Affinity DataIC50: 66nMAssay Description:Antagonist activity at NR1/NR2B receptor assessed as inhibition of Glu/Gly induced Ca2+ influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50083351(4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phen...)
Affinity DataIC50: 190nMAssay Description:Antagonist activity at wild type NR1/NR2B receptor expressed in Xenopus oocytes assessed as inhibition of agonist-induced current amplitude by two-el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tcg Lifesciences

Curated by ChEMBL
LigandPNGBDBM50083351(4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phen...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Indian Institute of Technology (Banaras Hindu University)

Curated by ChEMBL
LigandPNGBDBM50083351(4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phen...)
Affinity DataIC50: 110nMAssay Description:Negative allosteric modulation of human GluN2B receptor expressed in xenopus laevis oocytes assessed as reduction in 3 uM glycine-induced channel cur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target1,3-beta-glucan synthase(Yeast)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50083351(4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phen...)
Affinity DataIC50: 3.95E+4nMAssay Description:Negative allosteric modulation of human GluN2A receptor expressed in xenopus laevis oocytes assessed as reduction in 3 uM glycine-induced channel cur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50083351(4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phen...)
Affinity DataIC50: 2.91E+4nMAssay Description:Negative allosteric modulation of human GluN2C receptor expressed in xenopus laevis oocytes assessed as reduction in 3 uM glycine-induced channel cur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50083351(4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phen...)
Affinity DataIC50: 7.59E+4nMAssay Description:Negative allosteric modulation of human GluN2D receptor expressed in xenopus laevis oocytes assessed as reduction in 3 uM glycine-induced channel cur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Farmaceutiche Ed Ambientali (Chibiofaram) Universit£

Curated by ChEMBL
LigandPNGBDBM50083351(4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phen...)
Affinity DataIC50: 47nMAssay Description:Displacement of [3H]ifenprodil from Wistar rat cerebral cortex GluN2B receptor after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Farmaceutiche Ed Ambientali (Chibiofaram) Universit£

Curated by ChEMBL
LigandPNGBDBM50083351(4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phen...)
Affinity DataIC50: 20nMAssay Description:Displacement of [3H]Ifenprodil from NMDA receptor GluN2B subunit in Wistar rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50083351(4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phen...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]-(+)-pentazocine from guinea pig brain sigma1 receptor after 150 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Indian Institute of Technology (Banaras Hindu University)

Curated by ChEMBL
LigandPNGBDBM50083351(4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phen...)
Affinity DataKi:  5.80nMAssay Description:Displacement of [3H]ifenprodil from human GluN2B expressed in mouse L-M(TK-) cell membrane coexpressing GluN1a assessed as inhibition constant measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Indian Institute of Technology (Banaras Hindu University)

Curated by ChEMBL
LigandPNGBDBM50083351(4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phen...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]ifenprodil from human recombinant GluN2B expressed in mouse L(tk-) cell membranes co-expressing GluN1a incubated for 120 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Indian Institute of Technology (Banaras Hindu University)

Curated by ChEMBL
LigandPNGBDBM50083351(4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phen...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]ifenprodil from human GluN2B expressed in mouse L(tk-) cells co-expressing GluN1a after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Indian Institute of Technology (Banaras Hindu University)

Curated by ChEMBL
LigandPNGBDBM50083351(4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phen...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]ifenprodil from recombinant human GluN2B NMDA receptor (unknown origin) expressed in dexamethasone-induced mouse L-M(TK-) cell af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Indian Institute of Technology (Banaras Hindu University)

Curated by ChEMBL
LigandPNGBDBM50083351(4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phen...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]ifenprodil from human GluN2B expressed in mouse L(tk-) cell membranes co-expressing GluN1a incubated for 2 hrs by scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Indian Institute of Technology (Banaras Hindu University)

Curated by ChEMBL
LigandPNGBDBM50083351(4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phen...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]ifenprodil from GluN2B (unknown origin) expressed in mouse L(tk-) cell membranes co-expressing GluN1a incubated for 120 mins by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Indian Institute of Technology (Banaras Hindu University)

Curated by ChEMBL
LigandPNGBDBM50083351(4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phen...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]Ifenprodil from GluN2B receptor (unknown origin) expressed in mouse L(tk-) cell membranes incubated for 120 mins measured for 5 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50083351(4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phen...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]-ifenprodil from GluN1a/GluN2B (unknown origin) expressed in L(tk-) cell membranes after 120 mins by scintillation counting analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Farmaceutiche Ed Ambientali (Chibiofaram) Universit£

Curated by ChEMBL
LigandPNGBDBM50083351(4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phen...)
Affinity DataKi:  17nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Farmaceutiche Ed Ambientali (Chibiofaram) Universit£

Curated by ChEMBL
LigandPNGBDBM50083351(4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phen...)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]ifenprodil from Wistar rat cerebral cortex glutamate NMDA receptor GluN2B subunit after 120 mins by scintillation counting analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSigma intracellular receptor 2(Rat)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50083351(4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phen...)
Affinity DataKi:  98nMAssay Description:Displacement of [3H]-di-o-tolylguanidine from sigma-2 receptor in rat liver membranes incubated for 120 mins measured for 5 mins by scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50083351(4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phen...)
Affinity DataKi:  98nMAssay Description:Displacement of [3H]-DTG from S2R in rat liver membranes after 120 mins by scintillation counting assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50083351(4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phen...)
Affinity DataKi:  98nMAssay Description:Displacement of [3H]di-o-tolylguanidine from sigma2 receptor in rat liver membranes measured after 120 mins by solid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50083351(4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phen...)
Affinity DataKi:  98nMAssay Description:Displacement of [3H]di-o-tolylguanidine from sigma2 receptor in rat liver membrane assessed as inhibition constant measured after 120 mins by scintil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetSigma intracellular receptor 2(Rat)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50083351(4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phen...)
Affinity DataKi:  98nMAssay Description:Displacement of [3H]DTG from sigma 2 receptor in rat liver membranes measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetSigma intracellular receptor 2(Rat)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50083351(4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phen...)
Affinity DataKi:  98nMAssay Description:Displacement of [3H]DTG from sigma 2 receptor in rat liver membranes incubated for 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50083351(4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phen...)
Affinity DataKi:  98nMAssay Description:Displacement of [3H]-di-o-tolylguanidine from sigma2 receptor in rat liver membranes incubated for 120 mins in the presence of sigma1 receptor ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50083351(4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phen...)
Affinity DataKi:  98nMAssay Description:Displacement of [3H]-di-o-tolylguanidine from sigma2 receptor in rat liver membranes incubated for 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50083351(4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phen...)
Affinity DataKi:  98nMAssay Description:Displacement of [3H]-Di-o-tolylguanidine from sigma-2 receptor in rat liver membranes after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50083351(4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phen...)
Affinity DataKi:  98nMAssay Description:Displacement of [3H]DTG from sigma2 receptor in rat liver membranes after 120 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50083351(4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phen...)
Affinity DataKi:  98nMAssay Description:Displacement of [3H]-DTG from sigma 2 receptor in rat liver membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50083351(4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phen...)
Affinity DataKi:  125nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membranes incubated for 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50083351(4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phen...)
Affinity DataKi:  125nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain cortex membranes after 120 mins by microbeta scintillation counting met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50083351(4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phen...)
Affinity DataKi:  125nMAssay Description:Displacement of [3H]-(+)-pentazocine from Sigma1 receptor in guinea pig cortex membranes incubated for 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50083351(4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phen...)
Affinity DataKi:  125nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain cortex membrane after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50083351(4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phen...)
Affinity DataKi:  125nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50083351(4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phen...)
Affinity DataKi:  125nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain cortex membranes incubated for 120 mins measured for 5 mins by scintil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50083351(4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phen...)
Affinity DataKi:  125nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain cortex membranes incubated for 120 mins by solid scintillation counting...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50083351(4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phen...)
Affinity DataKi:  125nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane assessed as inhibition constant measured after 120 mins by sci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50083351(4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phen...)
Affinity DataKi:  125nMAssay Description:Displacement of [3H]-(+)pentazocine from sigma-1 receptor in guinea pig brain membranes after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50083351(4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phen...)
Affinity DataKi:  125nMAssay Description:Displacement of [3H](+)-pentazocine from S1R in guinea pig brain cortex membranes after 120 mins by scintillation counting assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50083351(4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phen...)
Affinity DataKi:  125nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in guinea pig brain membranes after 180 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2016
Entry Details Article
PubMed
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