BDBM50170339 1-(1-Pentyl-1H-indol-3-yl)-2-o-tolyl-ethanone::1-(1-pentyl-1H-indol-3-yl)-2-o-tolylethanone::CHEMBL364820::JWH-251

SMILES CCCCCn1cc(C(=O)Cc2ccccc2C)c2ccccc12

InChI Key InChIKey=YBIPNGRKUAVSBG-UHFFFAOYSA-N

Data  4 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50170339   

TargetCannabinoid receptor 2(Human)
Clemson University

Curated by ChEMBL
LigandPNGBDBM50170339(JWH-251 | 1-(1-pentyl-1H-indol-3-yl)-2-o-tolyletha...)
Affinity DataEC50:  8.30nMAssay Description:Effective concentration for stimulation of [35S]GTP-gamma-S, binding at CB2 receptor in presence of 3 uM CP-55940More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
Clemson University

Curated by ChEMBL
LigandPNGBDBM50170339(JWH-251 | 1-(1-pentyl-1H-indol-3-yl)-2-o-tolyletha...)
Affinity DataEC50:  29nMAssay Description:Effective concentration for stimulation of [35S]GTP-gamma-S binding at CB1 receptor in presence of 10 uM WIN-55212-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
Clemson University

Curated by ChEMBL
LigandPNGBDBM50170339(JWH-251 | 1-(1-pentyl-1H-indol-3-yl)-2-o-tolyletha...)
Affinity DataKi:  29nMAssay Description:Binding affinity to displace [3H]CP-55940 from CB1 receptor of rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
Clemson University

Curated by ChEMBL
LigandPNGBDBM50170339(JWH-251 | 1-(1-pentyl-1H-indol-3-yl)-2-o-tolyletha...)
Affinity DataKi:  29.0nMAssay Description:Displacement of [3H]CP-55940 from CB1 receptor in rat brain by filtration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Clemson University

Curated by ChEMBL
LigandPNGBDBM50170339(JWH-251 | 1-(1-pentyl-1H-indol-3-yl)-2-o-tolyletha...)
Affinity DataKi:  146nMAssay Description:Binding affinity to displace [3H]CP-55940 from cloned human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Clemson University

Curated by ChEMBL
LigandPNGBDBM50170339(JWH-251 | 1-(1-pentyl-1H-indol-3-yl)-2-o-tolyletha...)
Affinity DataKi:  146nMAssay Description:Displacement of [3H]CP-55940 from human cloned CB2 receptor by filtration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed