BDBM50649917 INCB-018424 PHOSPHATE::INCB-018424 SALT::INCB-18424 PHOSPHATE::INCB018424 PHOSPHATE::INCB018424 SALT::Jakafi::Jakavi::Opzelura::Ruxolitinib (as phosphate)::Ruxolitinib monophosphate::Ruxolitinib phosphate

SMILES N#CC[C@H](C1CCCC1)n1cc(-c2ncnc3[nH]ccc23)cn1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50649917   

TargetTyrosine-protein kinase JAK2(Human)
Jilin University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50649917BDBM50649917(Ruxolitinib (as phosphate) | Ruxolitinib phosphate...)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Jilin University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50649917BDBM50649917(Ruxolitinib (as phosphate) | Ruxolitinib phosphate...)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed