BDBM782402 KPGC01S42::US12448359, Compound 4e

SMILES COc1cc(OCc2cccc(-c3ccccc3)c2C)cc(OC)c1CN1CCC[C@H](C(=O)O)C1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 782402   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Purdue Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 782402BDBM782402(KPGC01S42 | US12448359, Compound 4e)
Affinity DataIC50: 1.26E+3nMAssay Description:The HTRF assay confirmed that compound 4b has an IC50 of 339.9 nM (see Experimental Section for details) to inhibit PD-1/PD-L1 interaction (FIG. 5D)....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/9/2026
Entry Details
US Patent