BDBM50324736 3-(2-aminoethyl)-5-(2-methoxybenzylidene)thiazolidine-2,4-dione::CHEMBL1222279::L-136468

SMILES COc1ccccc1\C=C1/SC(=O)N(CCN)C1=O

InChI Key InChIKey=NSCDHFLVIQHIHK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50324736   

TargetCDGSH iron-sulfur domain-containing protein 1(Human)
Northeast Ohio Medical University

Curated by ChEMBL
LigandPNGBDBM50324736(L-136468 | 3-(2-aminoethyl)-5-(2-methoxybenzyliden...)
Affinity DataIC50: 8.23E+4nMAssay Description:Displacement of [3H]-rosiglitazone from human recombinant C-terminal His-tagged cytosolic domain of mitoNEET (32-108) by scintillation proximity assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50324736(L-136468 | 3-(2-aminoethyl)-5-(2-methoxybenzyliden...)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of human recombinant MAOB by amplex red assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2013
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50324736(L-136468 | 3-(2-aminoethyl)-5-(2-methoxybenzyliden...)
Affinity DataIC50: 2.99E+4nMAssay Description:Inhibition of human recombinant MAOA assessed as inhibition of kynuramine conversion to fluorescent metabolite 4-hydroxyquinoline by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2013
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50324736(L-136468 | 3-(2-aminoethyl)-5-(2-methoxybenzyliden...)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of human recombinant MAO-B after 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed