BDBM50324737 3-(2-aminoethyl)-5-(4-(dimethylamino)benzylidene)thiazolidine-2,4-dione::CHEMBL1222280::L-136662

SMILES CN(C)c1ccc(\C=C2/SC(=O)N(CCN)C2=O)cc1

InChI Key InChIKey=BOQIVKJIDMTNLR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50324737   

TargetAmine oxidase [flavin-containing] B(Human)
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50324737(L-136662 | 3-(2-aminoethyl)-5-(4-(dimethylamino)be...)
Affinity DataIC50: 195nMAssay Description:Inhibition of human recombinant MAOB by amplex red assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2013
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50324737(L-136662 | 3-(2-aminoethyl)-5-(4-(dimethylamino)be...)
Affinity DataIC50: 6.88E+3nMAssay Description:Inhibition of human recombinant MAOA assessed as inhibition of kynuramine conversion to fluorescent metabolite 4-hydroxyquinoline by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2013
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50324737(L-136662 | 3-(2-aminoethyl)-5-(4-(dimethylamino)be...)
Affinity DataIC50: 195nMAssay Description:Inhibition of human recombinant MAO-B after 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50324737(L-136662 | 3-(2-aminoethyl)-5-(4-(dimethylamino)be...)
Affinity DataIC50: 195nMAssay Description:Inhibition of recombinant human MAO-BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed