BDBM50049179 4'-(4-Ethyl-5-formyl-2-propyl-imidazol-1-ylmethyl)-biphenyl-2-sulfonic acid benzoylamide::CHEMBL59957::L-161570

SMILES CCCc1nc(CC)c(C=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1

InChI Key InChIKey=RGFKKMLDMSOCFY-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50049179   

TargetType-1 angiotensin II receptor(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50049179(L-161570 | 4'-(4-Ethyl-5-formyl-2-propyl-imidazol-...)
Affinity DataIC50: 2.40nMAssay Description:In vitro inhibitory activity against Angiotensin II receptor, type 1 to displace 125I-Sar,Ile8-AII in rabbit aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetType-1 angiotensin II receptor(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50049179(L-161570 | 4'-(4-Ethyl-5-formyl-2-propyl-imidazol-...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of Angiotensin II receptor, type 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetType-2 angiotensin II receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50049179(L-161570 | 4'-(4-Ethyl-5-formyl-2-propyl-imidazol-...)
Affinity DataIC50: 500nMAssay Description:In vitro inhibitory activity against angiotensin II (AT2) receptor to displace 125I-Sar,Ile8-AII in rat midbrainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetType-2 angiotensin II receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50049179(L-161570 | 4'-(4-Ethyl-5-formyl-2-propyl-imidazol-...)
Affinity DataIC50: 500nMAssay Description:Displacement of [125I]- Ang II from angiotensin II AT2 receptor in rat adrenal cortical microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetType-2 angiotensin II receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50049179(L-161570 | 4'-(4-Ethyl-5-formyl-2-propyl-imidazol-...)
Affinity DataIC50: 500nMAssay Description:Inhibitory activity at Angiotensin II type 2 receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
LigandPNGBDBM50049179(L-161570 | 4'-(4-Ethyl-5-formyl-2-propyl-imidazol-...)
Affinity DataIC50: 2.40nMAssay Description:Displacement of [125I]- Ang II from angiotensin II AT1 receptor in rat adrenal cortical microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article