BDBM50002831 (2R,5R)-2,5-Bis-(3,4,5-trimethoxy-phenyl)-tetrahydro-furan::(2S,5S)-2,5-Bis-(3,4,5-trimethoxy-phenyl)-tetrahydro-furan::(E)-(1R,2R,3R,5R,12S,13R,16S)-16-Hydroxymethyl-5,9,12,13-tetramethyl-4-oxa-tricyclo[10.3.1.0*3,5*]hexadec-8-en-2-ol::(L 652731)2,5-Bis-(3,4,5-trimethoxy-phenyl)-tetrahydro-furan::2,5-Bis-(3,4,5-trimethoxy-phenyl)-tetrahydro-furan::2,5-Bis-(3,4,5-trimethoxy-phenyl)-tetrahydro-furan(L-652,731)::2,5-Bis-(3,4,5-trimethoxy-phenyl)-tetrahydro-furan(L-652731)::CHEMBL297624::L-652731

SMILES COc1cc(cc(OC)c1OC)[C@@H]1CC[C@H](O1)c1cc(OC)c(OC)c(OC)c1

InChI Key InChIKey=YCCPYTPBHUIHGW-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50002831   

TargetPlatelet-activating factor receptor(Human)
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50002831(CHEMBL297624 | (L 652731)2,5-Bis-(3,4,5-trimethoxy...)
Affinity DataIC50: 1.50E+3nMAssay Description:Concentration required to cause 50% inhibition of platelet activating factor (PAF)-induced platelet aggregation of human platelet rich plasma when ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50002831(CHEMBL297624 | (L 652731)2,5-Bis-(3,4,5-trimethoxy...)
Affinity DataIC50: 20nMAssay Description:Inhibition of PAF receptor binding to rabbit platelet plasma membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Human)
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50002831(CHEMBL297624 | (L 652731)2,5-Bis-(3,4,5-trimethoxy...)
Affinity DataKi:  215nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2011
Entry Details
PubMed
TargetPlatelet-activating factor receptor(Human)
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50002831(CHEMBL297624 | (L 652731)2,5-Bis-(3,4,5-trimethoxy...)
Affinity DataKi:  268nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2011
Entry Details
PubMed