BDBM36720 LG190155

SMILES CCC(CC)(c1ccc(OCC(=O)C(C)(C)C)c(C)c1)c1ccc(OCC(=O)C(C)(C)C)c(C)c1

InChI Key InChIKey=WBLVHHHWMJPSGY-UHFFFAOYSA-N

Data  1 KI  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 36720   

TargetVitamin D-binding protein(Human)
Ligand Pharmaceuticals

LigandPNGBDBM36720(LG190155)
Affinity DataIC50: 1.00E+3nMpH: 7.4 T: 2°CAssay Description:DBP competition binding assay were done using human serum (Scantibodies) or rat serum (Gibco-BRL).More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2011
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM36720(LG190155)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human androgen receptor expressed in HEK293 cells assessed as inhibition of transcriptional activity by luciferase and beta-ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM36720(LG190155)
Affinity DataEC50:  40nMAssay Description:Agonist activity at VDR (unknown origin) by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAndrogen receptor(Mouse)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM36720(LG190155)
Affinity DataIC50: 1.90E+3nMAssay Description:Androgen antagonistic activity as inhibitory concentration against testosterone-induced SC-3 cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM36720(LG190155)
Affinity DataEC50:  590nMAssay Description:Agonist activity at vitamin D3 receptor in human HL-60 cells assessed as induction of cell differentiation after 96 hrs by NBT dye-based microscopic ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM36720(LG190155)
Affinity DataKi: >1.00E+3nM ΔG°: >-7.60kcal/molepH: 7.5 T: 2°CAssay Description:VDR in vitro ligand-binding assay using human VDR constructed into a yeast expression plasmid.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2011
Entry Details Article
PubMed