BDBM36333 LI-0::Legumain Inhibitor -0

SMILES CC(=O)N1CCC[C@H]1C(=O)N[C@H](CCOC(=O)c1c(C)cccc1C)CC(O)=O

InChI Key InChIKey=LEZYKWQCDKWUNG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 36333   

TargetLegumain(Mouse)
Stanford University

LigandPNGBDBM36333(LI-0 | Legumain Inhibitor -0)
Affinity DataIC50: 704nMpH: 5.8 T: 2°CAssay Description:IC50 measurements and enzyme kinetics assays were performed on a Spectramax M5 fluorescent plate reader (Molecular Devices).More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2011
Entry Details Article
PubMed
TargetCathepsin B(Mouse)
Stanford University

LigandPNGBDBM36333(LI-0 | Legumain Inhibitor -0)
Affinity DataIC50: 1.00E+6nMpH: 6.25 T: 2°CAssay Description:IC50 measurements and enzyme kinetics assays were performed on a Spectramax M5 fluorescent plate reader (Molecular Devices).More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2011
Entry Details Article
PubMed
TargetProcathepsin L(Mouse)
Stanford University

LigandPNGBDBM36333(LI-0 | Legumain Inhibitor -0)
Affinity DataIC50: 1.00E+6nMpH: 6.25 T: 2°CAssay Description:IC50 measurements and enzyme kinetics assays were performed on a Spectramax M5 fluorescent plate reader (Molecular Devices).More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2011
Entry Details Article
PubMed
TargetCaspase-3(Mouse)
Stanford University

LigandPNGBDBM36333(LI-0 | Legumain Inhibitor -0)
Affinity DataIC50: 2.80E+3nMpH: 7.4 T: 2°CAssay Description:IC50 measurements and enzyme kinetics assays were performed on a Spectramax M5 fluorescent plate reader (Molecular Devices).More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2011
Entry Details Article
PubMed