BDBM50092157 (4R,5S)-3-Oxo-4,5-diphenyl-pyrazolidine-1-carboxylic acid (4-bromo-phenyl)-amide::(4R,5S)-N-(4-bromophenyl)-3-oxo-4,5-diphenylpyrazolidine-1-carboxamide::3-Oxo-4,5-diphenyl-pyrazolidine-1-carboxylic acid (4-bromo-phenyl)-amide(LY288512)::CHEMBL117281::LY-288512

SMILES Brc1ccc(NC(=O)N2NC(=O)[C@@H]([C@H]2c2ccccc2)c2ccccc2)cc1

InChI Key InChIKey=LMUQHXHWJWQXSD-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50092157   

TargetCholecystokinin receptor type A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50092157((4R,5S)-N-(4-bromophenyl)-3-oxo-4,5-diphenylpyrazo...)
Affinity DataIC50: 6.40E+3nMAssay Description:The compound was tested for its activity to inhibit the binding of [3H]-L-364,718 to Cholecystokinin type A receptor in rat pancreasMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50092157((4R,5S)-N-(4-bromophenyl)-3-oxo-4,5-diphenylpyrazo...)
Affinity DataIC50: 370nMpH: 7.4Assay Description:The compound was tested for its activity to inhibit the binding of [125I]CCK-8 to Cholecystokinin type B receptor in mouse brain at a pH of 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetCholecystokinin receptor type A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50092157((4R,5S)-N-(4-bromophenyl)-3-oxo-4,5-diphenylpyrazo...)
Affinity DataIC50: 6.40E+3nMAssay Description:Half maximal inhibition of specific binding of [125I]-Bolton-Hunter CCK-8 to Cholecystokinin type A receptor in the rat pancreasMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
LigandPNGBDBM50092157((4R,5S)-N-(4-bromophenyl)-3-oxo-4,5-diphenylpyrazo...)
Affinity DataIC50: 370nMAssay Description:Half maximal inhibition of specific binding of [125I]Bolton-Hunter CCK-8 to Cholecystokinin type B receptor in the mouse cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Guinea pig)
James Black Foundation

Curated by ChEMBL
LigandPNGBDBM50092157((4R,5S)-N-(4-bromophenyl)-3-oxo-4,5-diphenylpyrazo...)
Affinity DataKi:  2.00E+4nMAssay Description:Displacement of [125I]BH-CCK-8S from CC1 receptor expressed in guinea pig pancreatic cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed