BDBM50282666 (S)-N*1*-[(1S,2S)-1-Benzyl-3-(2-tert-butylcarbamoyl-phenyl)-2-hydroxy-propyl]-2-[(quinoline-2-carbonyl)-amino]-succinamide::CHEMBL281922::LY-289612

SMILES CC(C)(C)NC(=O)c1ccccc1C[C@H](O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)c1ccc2ccccc2n1

InChI Key InChIKey=RHADMHOBZRGRTJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50282666   

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50282666(LY-289612 | (S)-N*1*-[(1S,2S)-1-Benzyl-3-(2-tert-b...)
Affinity DataIC50: 320nMAssay Description:Concentration required for in vitro inhibition of HIV-1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article