BDBM50239015 CHEBI:6993::MK-476::Montelukast Sodium::Singulair

SMILES CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC([O-])=O)CC1)c1cccc(C=Cc2ccc3ccc(Cl)cc3n2)c1

InChI Key InChIKey=UCHDWCPVSPXUMX-UHFFFAOYSA-M

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50239015   

TargetCysteinyl leukotriene receptor 1(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50239015(CHEBI:6993 | MK-476 | Montelukast Sodium | Singula...)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of cysteinyl leukotriene receptor 1 (unknown origin) expressed in HEK293 cell membranes after 45 mins by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2019
Entry Details Article
PubMed
TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Northwest University

Curated by ChEMBL
LigandPNGBDBM50239015(CHEBI:6993 | MK-476 | Montelukast Sodium | Singula...)
Affinity DataKd:  13nMAssay Description:Binding affinity to immobilized Halo tag-fused CysLT receptor (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as dissociation rate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed