BDBM50365735 CHEMBL33859::MKT-077::US20230414581, Compound 39

SMILES CCn1\c(=C\c2cccc[n+]2CC)s\c(=C2\Sc3ccccc3N2C)c1=O

InChI Key InChIKey=QLYHOWIZHHZGPV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50365735   

TargetTelomerase reverse transcriptase(Human)
Tianjin Key Laboratory On Technologies Enabling Development of Clinical Therapeutics and Diagnostics

Curated by ChEMBL
LigandPNGBDBM50365735(MKT-077 | CHEMBL33859 | US20230414581, Compound 39)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of telomeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetNAD(+) hydrolase SARM1(Human)
Artivila Biopharma

US Patent
LigandPNGBDBM50365735(MKT-077 | CHEMBL33859 | US20230414581, Compound 39)
Affinity DataIC50: 5.50E+3nMAssay Description:First, 200 μM of the compound was added to a 50 mM Tris-HCl (pH 7.5) solution containing 0.05 μg/ml dN-SARM1. Then half of the mixture was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2024
Entry Details
Go to US Patent