BDBM154518 ML395 (6)

SMILES O=C(NCCN1CCC2(CC1)N(Cc1cccnc1)CNC2=O)c1ccc2ccccc2c1

InChI Key InChIKey=VBJYNYMKFQGJCH-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 154518   

TargetPhospholipase D1(Human)
Vanderbilt University

LigandPNGBDBM154518(ML395 (6))
Affinity DataIC50: 3.00E+4nMAssay Description:Cells were seeded into 12-well tissue culture plates to reach 90% confluence at the time of assay. All cell types, aside from the HEK293-gfpPLD2 cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2015
Entry Details Article
PubMed
TargetPhospholipase D2(Human)
Vanderbilt University

LigandPNGBDBM154518(ML395 (6))
Affinity DataIC50: 380nMAssay Description:Cells were seeded into 12-well tissue culture plates to reach 90% confluence at the time of assay. All cell types, aside from the HEK293-gfpPLD2 cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2015
Entry Details Article
PubMed
TargetPhospholipase D(Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22...)
Vanderbilt University

LigandPNGBDBM154518(ML395 (6))
Affinity DataIC50: 2.00E+4nMpH: 7.5Assay Description:In brief, 6 nM purified PldA was incubated with liposomes containing 90 μM 1,2-dioleoyl-sn-glycero-3-phospho-(1′-rac-glycerol), 10 μM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2015
Entry Details Article
PubMed
TargetPhospholipase D1(Human)
Vanderbilt University

LigandPNGBDBM154518(ML395 (6))
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of PLD1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetPhospholipase D2(Human)
Vanderbilt University

LigandPNGBDBM154518(ML395 (6))
Affinity DataIC50: 360nMAssay Description:Inhibition of PLD2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed