BDBM50249581 CHEBI:6700::Matrine

SMILES [H][C@]12CCCN3CCC[C@]([H])([C@@]4([H])CCCC(=O)N4C1)[C@]23[H]

InChI Key InChIKey=ZSBXGIUJOOQZMP-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50249581   

TargetAdvanced glycosylation end product-specific receptor(Human)
King'S College London

Curated by ChEMBL
LigandPNGBDBM50249581(CHEBI:6700 | Matrine)
Affinity DataKd:  2.40E+7nMAssay Description:Inhibition of amyloid beta binding to human RAGE domain V (Met1 to Ala 344 residues) expressed in HEK293 cells after 10 mins by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2019
Entry Details Article
PubMed
TargetAdvanced glycosylation end product-specific receptor(Human)
King'S College London

Curated by ChEMBL
LigandPNGBDBM50249581(CHEBI:6700 | Matrine)
Affinity DataKd:  2.39E+7nMAssay Description:Binding affinity to human RAGE by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed