BDBM772149 Method A::US20250289807, Example 10

SMILES C[C@H](NC(=O)c1cc2ccc(-c3nccc(Nc4ccc(-c5cnc[nH]5)cc4)n3)cc2n1CC1COC1)C(F)(F)F

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 772149   

TargetRho-associated protein kinase 2(Human)
Graviton Bioscience

US Patent
LigandPNGBDBM772149(Method A | US20250289807, Example 10)
Affinity DataIC50: 1.81E+3nMAssay Description:Each plate contained a positive control (1 μM Comp. A for ROCK2 and 1 μM RKI-1447 for ROCK1); a vehicle control (1% DMSO); a blank control (kinase re...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/4/2026
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Graviton Bioscience

US Patent
LigandPNGBDBM772149(Method A | US20250289807, Example 10)
Affinity DataIC50: 4.00E+3nMAssay Description:Each plate contained a positive control (1 μM Comp. A for ROCK2 and 1 μM RKI-1447 for ROCK1); a vehicle control (1% DMSO); a blank control (kinase re...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/4/2026
Entry Details
US Patent