BDBM60419 BDBM50295658::NAM

SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCCN1C(=O)C=CC1=O

InChI Key InChIKey=GZNZRHSGGQUYAP-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 60419   

TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM60419(NAM | BDBM50295658)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of Wistar rat brain FAAHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM60419(NAM | BDBM50295658)
Affinity DataIC50: 140nMAssay Description:Inhibition of human recombinant MGL by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM60419(NAM | BDBM50295658)
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibition of human MGLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Louvain Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM60419(NAM | BDBM50295658)
Affinity DataIC50: 2.18E+3nMAssay Description:Inhibition of human FAAHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM60419(NAM | BDBM50295658)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FAAH in Sprague-Dawley rat brain microsomes assessed as N-(2-hydroxyethyl)-4-pyren-1-ylbutanamide conversion to 4-pyren-1-ylbutanoic ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM60419(NAM | BDBM50295658)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human MAGL expressed in Escherichia coli using 6-methoxy-4-methylcoumarin ester as substrate after 3 hrs by mass spectroscopic analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of M£Nster

Curated by ChEMBL
LigandPNGBDBM60419(NAM | BDBM50295658)
Affinity DataIC50: 140nMAssay Description:Inhibition of MAGL in rat cerebellar membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of M£Nster

Curated by ChEMBL
LigandPNGBDBM60419(NAM | BDBM50295658)
Affinity DataIC50: 140nMAssay Description:Inhibition of MAGL from Wistar rat brain using 2-monooleoyl[1,2,3-H]glycerol as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of M£Nster

Curated by ChEMBL
LigandPNGBDBM60419(NAM | BDBM50295658)
Affinity DataIC50: 140nMAssay Description:Inhibition of rat cerebellar membranes MAGL-like activity preincubated for 30 mins followed by 2-AG substrate addition after 90 mins by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM60419(NAM | BDBM50295658)
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibition of human cerebellar membranes MAGL-like activity preincubated for 30 mins followed by 2-AG substrate addition after 90 mins by HPLC analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed