BDBM50231744 CHEMBL399160::NPS 2390::quinoxaline-2-carboxylic acid adamantan-1-ylamide

SMILES O=C(NC12CC3CC(CC(C3)C1)C2)c1cnc2ccccc2n1

InChI Key

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50231744   

TargetMetabotropic glutamate receptor 1(Rat)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231744(NPS 2390 | CHEMBL399160 | quinoxaline-2-carboxylic...)
Affinity DataIC50: 5nMAssay Description:Antagonist activity at rat mGluR1 expressed in cerebellar granule cells assessed as accumulation of [3H]inositol phosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231744(NPS 2390 | CHEMBL399160 | quinoxaline-2-carboxylic...)
Affinity DataKi:  1.36nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231744(NPS 2390 | CHEMBL399160 | quinoxaline-2-carboxylic...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2012
Entry Details Article
PubMed