BDBM50056878 CHEMBL174455::N-[3-(4-Chloro-phenyl)-3-hydroxy-3-phenyl-propionyl]-2-hydroxy-benzamide::NSC-632901

SMILES Oc1ccccc1C(=O)NC(=O)CC(O)(c1ccccc1)c1ccc(Cl)cc1

InChI Key InChIKey=DDEPSTRGUUWAKZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50056878   

TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50056878(NSC-632901 | N-[3-(4-Chloro-phenyl)-3-hydroxy-3-ph...)
Affinity DataIC50: 1.01E+5nMAssay Description:Inhibitory concentration against purified recombinant integrase by strand transfer in vitro assay (experiment 1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50056878(NSC-632901 | N-[3-(4-Chloro-phenyl)-3-hydroxy-3-ph...)
Affinity DataIC50: 1.42E+5nMAssay Description:Inhibitory concentration against purified recombinant integrase by strand transfer in vitro assay (experiment 2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50056878(NSC-632901 | N-[3-(4-Chloro-phenyl)-3-hydroxy-3-ph...)
Affinity DataIC50: 1.82E+5nMAssay Description:Inhibitory concentration against purified recombinant integrase by 3'-processing in vitro assay (experiment 1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50056878(NSC-632901 | N-[3-(4-Chloro-phenyl)-3-hydroxy-3-ph...)
Affinity DataIC50: 2.38E+5nMAssay Description:Inhibitory concentration against purified recombinant integrase by 3'-processing in vitro assay (experiment 2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed