BDBM50059961 2-(3-Chloro-phenyl)-6-methyl-1H-[1,8]naphthyridin-4-one::2-(3-chlorophenyl)-6-methyl-1,8-naphthyridin-4(1H)-one::CHEMBL49827::NSC-679036

SMILES Cc1cnc2nc(cc(O)c2c1)-c1cccc(Cl)c1

InChI Key InChIKey=FSWIIQLXZOJBSF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50059961   

TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50059961(2-(3-Chloro-phenyl)-6-methyl-1H-[1,8]naphthyridin-...)
Affinity DataIC50: 724nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50059961(2-(3-Chloro-phenyl)-6-methyl-1H-[1,8]naphthyridin-...)
Affinity DataIC50: 720nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50059961(2-(3-Chloro-phenyl)-6-methyl-1H-[1,8]naphthyridin-...)
Affinity DataIC50: 720nMAssay Description:Concentration inhibiting tubulin polymerization (ITP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed