BDBM50298490 3a,5b,10-trimethyl-1,2,3a,4,5,5a,6,7,10,10a-decahydrocyclopenta[a]fluorene-3,8(5bH,10bH)-dione::CHEMBL583076::NSC-93358

SMILES CC1C2C3CCC(=O)C3(C)CCC2C2(C)CCC(=O)C=C12

InChI Key InChIKey=GYXFOOCGIVDNFH-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50298490   

TargetAromatase(Human)
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM50298490(NSC-93358 | 3a,5b,10-trimethyl-1,2,3a,4,5,5a,6,7,1...)
Affinity DataKi:  266nMAssay Description:Competitive inhibition of human placental aromatase by Lineweaver-Burke plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAromatase(Human)
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM50298490(NSC-93358 | 3a,5b,10-trimethyl-1,2,3a,4,5,5a,6,7,1...)
Affinity DataIC50: 274nMAssay Description:Inhibition of human placental aromatase assessed as conversion of [1-beta-3H]androstenedione to [1beta-3H]estrone after 20 mins by liquid scintillati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed