BDBM50021398 CHEBI:18088::FORMONONETIN::NSC-93360

SMILES COc1ccc(cc1)-c1coc2cc(O)ccc2c1=O

InChI Key InChIKey=HKQYGTCOTHHOMP-UHFFFAOYSA-N

Data  1 KI  15 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50021398   

TargetNeuraminidase(Influenza A virus)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50021398(NSC-93360 | CHEBI:18088 | FORMONONETIN)
Affinity DataIC50: 1.37E+3nMAssay Description:Inhibition of Influenza A virus (A/Puerto Rico/8/1934(H1N1)) neuraminidase by chemiluminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetSortase family protein(Staphylococcus aureus)
Indian Institute of Technology Delhi

Curated by ChEMBL
LigandPNGBDBM50021398(NSC-93360 | CHEBI:18088 | FORMONONETIN)
Affinity DataIC50: 7.49E+4nMAssay Description:Inhibition of recombinant Staphylococcus aureus ATCC 6538p SrtA expressed in Escherichia coli TOP10 using Dabcyl-QALPETGEE-Edans as substrate incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProteasome subunit beta type-5(Human)
Institute of Agricultural and Food Biotechnology

Curated by ChEMBL
LigandPNGBDBM50021398(NSC-93360 | CHEBI:18088 | FORMONONETIN)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of chymotrypsin-like activity of purified human erythrocyte 20S proteasome assessed as decrease in AMC hydrolysis using Suc-LLVY-AMC as su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Mouse)
Sunchon National University

Curated by ChEMBL
LigandPNGBDBM50021398(NSC-93360 | CHEBI:18088 | FORMONONETIN)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of mouse MAO-B preincubated for 15 mins followed by addition of kynuramine as substrate measured after 30 mins by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Mouse)
Sunchon National University

Curated by ChEMBL
LigandPNGBDBM50021398(NSC-93360 | CHEBI:18088 | FORMONONETIN)
Affinity DataIC50: 2.12E+4nMAssay Description:Inhibition of mouse MAO-A preincubated for 15 mins followed by addition of kynuramine as substrate measured after 30 mins by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Sunchon National University

Curated by ChEMBL
LigandPNGBDBM50021398(NSC-93360 | CHEBI:18088 | FORMONONETIN)
Affinity DataIC50: 3.12E+4nMAssay Description:Inhibition of recombinant human MAO-A expressed in baculovirus infected BTI insect cells preincubated for 10 mins followed by addition of kynuramine ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Sunchon National University

Curated by ChEMBL
LigandPNGBDBM50021398(NSC-93360 | CHEBI:18088 | FORMONONETIN)
Affinity DataIC50: 2.58E+4nMAssay Description:Inhibition of recombinant human MAO-B expressed in baculovirus infected BTI insect cells preincubated for 10 mins followed by addition of benzylamine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetUrease subunit beta(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Jishou University

Curated by ChEMBL
LigandPNGBDBM50021398(NSC-93360 | CHEBI:18088 | FORMONONETIN)
Affinity DataIC50: 2.00E+6nMAssay Description:Inhibition of Helicobacter pylori ATCC 43504 urease-mediated ammonia production preincubated for 1.5 hrs by indophenol methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50021398(NSC-93360 | CHEBI:18088 | FORMONONETIN)
Affinity DataIC50: 5.04E+3nMAssay Description:Inhibition of Influenza A virus (A/Hong Kong/1/1968(H3N2)) neuraminidase by chemiluminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetInterleukin-2(Human)
The Second People'S Hospital of Fujian Provinc

Curated by ChEMBL
LigandPNGBDBM50021398(NSC-93360 | CHEBI:18088 | FORMONONETIN)
Affinity DataKd:  5.47E+3nMAssay Description:Binding affinity to IL-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50021398(NSC-93360 | CHEBI:18088 | FORMONONETIN)
Affinity DataIC50: 3.04E+3nMAssay Description:Inhibition of Influenza A virus J/8178/09 neuraminidase by chemiluminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50021398(NSC-93360 | CHEBI:18088 | FORMONONETIN)
Affinity DataIC50: 5.04E+3nMAssay Description:Inhibition of oseltamivir-resistant Influenza A virus H1N1 B/55/08 neuraminidase by chemiluminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50021398(NSC-93360 | CHEBI:18088 | FORMONONETIN)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Influenza A Jiangsu/10/2003 virus neuraminidase activity by MUN-ANA substrate based fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50021398(NSC-93360 | CHEBI:18088 | FORMONONETIN)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Influenza A Jinan/15/90 H3N2 virus neuraminidase activity by MUN-ANA substrate based fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50021398(NSC-93360 | CHEBI:18088 | FORMONONETIN)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Influenza A PR/8/34 H1N1 virus neuraminidase activity by MUN-ANA substrate based fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetCytochrome P450 1A1(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50021398(NSC-93360 | CHEBI:18088 | FORMONONETIN)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP1A1 by EROD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetCytochrome P450 1B1(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM50021398(NSC-93360 | CHEBI:18088 | FORMONONETIN)
Affinity DataKi:  3.70E+3nMAssay Description:Inhibition of CYP1B1 in human liver microsomes coexpressing recombinant human cytochrome P450 oxidoreductase using 7-ethoxyresorufin as substrate aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2019
Entry Details Article
PubMed