BDBM517678 NY0642::US11124489, Compound 20

SMILES FC(F)(F)c1cc(NNC(C#N)C(=O)c2cc(on2)-c2ccc(Cl)cc2)ccc1Cl

InChI Key InChIKey=RCWCGERJAPUMNZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 517678   

TargetRap guanine nucleotide exchange factor 3(Human)
University Of Texas

US Patent
LigandPNGBDBM517678(NY0642 | US11124489, Compound 20)
Affinity DataIC50: 7.80E+3nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent