BDBM517680 NY0653::US11124489, Compound 22

SMILES COc1ccc(cc1)-c1cc(no1)C(=O)C(NNc1cccc(Cl)c1)C#N

InChI Key InChIKey=RSNOHXFDTNIRLE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 517680   

TargetRap guanine nucleotide exchange factor 3(Human)
University Of Texas

US Patent
LigandPNGBDBM517680(NY0653 | US11124489, Compound 22)
Affinity DataIC50: 1.14E+4nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent