BDBM50556205 BAY 1841788::BAY-1841788::BAY1841788::Darolutamide::Nubeqa::Odm-201
SMILES CC(O)c1cc(C(=O)N[C@@H](C)Cn2ccc(-c3ccc(C#N)c(Cl)c3)n2)n[nH]1
InChI Key InChIKey=BLIJXOOIHRSQRB-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 50556205
Affinity DataKi: 11nMAssay Description:Inhibition of androgen receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Displacement of [3H]-PDBu from human recombinant Protein kinase C deltaMore data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Inhibition of androgen receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Antagonist activity at Androgen receptor F877L mutant in human HEK293T cells cotransfected with MMTV-luc and renilla plasmid incubated for 24 hrs by ...More data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Antagonist activity at CMV-tagged full length wild type human AR expressed in HEK293 cells co-transfected with GRE-LUC and CMV-renilla LUC assessed a...More data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Antagonist activity at Androgen receptor F877L mutant expressed in human PC-3 cells co-expressing ARR2PB-luc by Dual-Luciferase reporter assayMore data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Antagonist activity at DHT-induced Androgen receptor W741C mutant in human PC-3 cells transfected with ARR2PB-Luc by Dual-Luciferase Reporter assayMore data for this Ligand-Target Pair
Affinity DataIC50: 454nMAssay Description:Antagonist activity at Androgen receptor F877L mutant in HEK293 cells in presence of R1881More data for this Ligand-Target Pair
Affinity DataIC50: 470nMAssay Description:Antagonist activity at DHT-induced Androgen receptor W741C mutant in human PC-3 cells transfected with ARR2PB-Luc by dual-luciferase reporter assayMore data for this Ligand-Target Pair
Affinity DataIC50: 696nMAssay Description:Antagonist activity at Androgen receptor F877L/T878A mutant expressed in human PC-3 cells co-expressing ARR2PB-luc by Dual-Luciferase reporter assayMore data for this Ligand-Target Pair
Affinity DataIC50: 850nMAssay Description:Antagonist activity at Androgen receptor W742C mutant in human HEK293T cells cotransfected with MMTV-luc and renilla plasmid incubated for 24 hrs by ...More data for this Ligand-Target Pair
Affinity DataIC50: 880nMAssay Description:Antagonist activity at DHT-induced Androgen receptor F876L/Y877A mutant in human PC-3 cells transfected with ARR2PB-Luc by dual-luciferase reporter a...More data for this Ligand-Target Pair
Affinity DataIC50: 1.05E+3nMAssay Description:Antagonist activity at DHT-induced Androgen receptor F876L/Y877A mutant in human PC-3 cells transfected with ARR2PB-Luc by Dual-Luciferase Reporter a...More data for this Ligand-Target Pair
Affinity DataKi: 4.23E+3nMAssay Description:Displacement of [3H]mibolerone from GST-tagged wild type AR ligand binding domain (unknown origin) incubated for 16 hrs by scintillation counting ana...More data for this Ligand-Target Pair