BDBM50637407 AEVI-006::ASP 7486::ASP-7486::ASP7486::CERC 006::CERC-006::CERC006::OSI027::Osi 027::Osi-027

SMILES COc1cccc2cc(-c3nc([C@H]4CC[C@H](C(=O)O)CC4)n4ncnc(N)c34)[nH]c12

InChI Key InChIKey=JROFGZPOBKIAEW-UHFFFAOYSA-N

Data  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50637407   

TargetSerine/threonine-protein kinase mTOR(Human)
China Jiliang University

Curated by ChEMBL
LigandPNGBDBM50637407(Osi 027 | Osi-027 | AEVI-006 | ASP 7486 | ASP-7486...)
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTarget of rapamycin complex subunit LST8(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50637407(Osi 027 | Osi-027 | AEVI-006 | ASP 7486 | ASP-7486...)
Affinity DataIC50: 22nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50637407(Osi 027 | Osi-027 | AEVI-006 | ASP 7486 | ASP-7486...)
Affinity DataIC50: 65nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
China Jiliang University

Curated by ChEMBL
LigandPNGBDBM50637407(Osi 027 | Osi-027 | AEVI-006 | ASP 7486 | ASP-7486...)
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandPNGBDBM50637407(Osi 027 | Osi-027 | AEVI-006 | ASP 7486 | ASP-7486...)
Affinity DataIC50: 1.30E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandPNGBDBM50637407(Osi 027 | Osi-027 | AEVI-006 | ASP 7486 | ASP-7486...)
Affinity DataIC50: 3.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandPNGBDBM50637407(Osi 027 | Osi-027 | AEVI-006 | ASP 7486 | ASP-7486...)
Affinity DataIC50: 420nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50637407(Osi 027 | Osi-027 | AEVI-006 | ASP 7486 | ASP-7486...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
China Jiliang University

Curated by ChEMBL
LigandPNGBDBM50637407(Osi 027 | Osi-027 | AEVI-006 | ASP 7486 | ASP-7486...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50637407(Osi 027 | Osi-027 | AEVI-006 | ASP 7486 | ASP-7486...)
Affinity DataIC50: 4.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50637407(Osi 027 | Osi-027 | AEVI-006 | ASP 7486 | ASP-7486...)
Affinity DataIC50: 4.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEphrin type-A receptor 2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50637407(Osi 027 | Osi-027 | AEVI-006 | ASP 7486 | ASP-7486...)
Affinity DataIC50: 4.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50637407(Osi 027 | Osi-027 | AEVI-006 | ASP 7486 | ASP-7486...)
Affinity DataIC50: 4.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50637407(Osi 027 | Osi-027 | AEVI-006 | ASP 7486 | ASP-7486...)
Affinity DataIC50: 3.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed