BDBM50296782 (1R,2S,3S,5S)-methyl 8-((E)-3-iodoallyl)-3-p-tolyl-8-azabicyclo[3.2.1]octane-2-carboxylate::CHEMBL538876::PE2I

SMILES COC(=O)[C@@H]1[C@H]2CC[C@@H](C[C@@H]1c1ccc(C)cc1)N2C\C=C\I

InChI Key

Data  7 KI  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50296782   

TargetSodium-dependent dopamine transporter(Rat)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50296782(CHEMBL538876 | PE2I | (1R,2S,3S,5S)-methyl 8-((E)-...)
Affinity DataKd:  4nMAssay Description:Binding affinity to rat DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50296782(CHEMBL538876 | PE2I | (1R,2S,3S,5S)-methyl 8-((E)-...)
Affinity DataKi:  16nMAssay Description:Displacement of [125I]PE2I from rat DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50296782(CHEMBL538876 | PE2I | (1R,2S,3S,5S)-methyl 8-((E)-...)
Affinity DataKi:  17nMAssay Description:Displacement of [3H]WIN35428 from human cloned DAT receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50296782(CHEMBL538876 | PE2I | (1R,2S,3S,5S)-methyl 8-((E)-...)
Affinity DataKi:  17nMAssay Description:Binding affinity to DAT (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50296782(CHEMBL538876 | PE2I | (1R,2S,3S,5S)-methyl 8-((E)-...)
Affinity DataKi:  18nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50296782(CHEMBL538876 | PE2I | (1R,2S,3S,5S)-methyl 8-((E)-...)
Affinity DataKi: >500nMAssay Description:Displacement of [3H]nisoxetine from human cloned NET receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Medical University of Vienna

Curated by ChEMBL
LigandPNGBDBM50296782(CHEMBL538876 | PE2I | (1R,2S,3S,5S)-methyl 8-((E)-...)
Affinity DataKi:  500nMAssay Description:Binding affinity to SERT (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50296782(CHEMBL538876 | PE2I | (1R,2S,3S,5S)-methyl 8-((E)-...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to NET (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed