BDBM50056315 CHEBI:17558::Quercitrin

SMILES C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC2=C(Oc3cc(cc(c3C2=O)O)O)c4ccc(c(c4)O)O)O)O)O

InChI Key InChIKey=OXGUCUVFOIWWQJ-UHFFFAOYSA-N

Data  1 KI  11 IC50

PDB links: 5 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50056315   

TargetNeuraminidase(Influenza A virus (strain A/USSR/90/1977 H1N1))
Freie Universitaet Berlin

Curated by ChEMBL
LigandPNGBDBM50056315(CHEBI:17558 | Quercitrin)
Affinity DataIC50: 1.21E+5nMAssay Description:Inhibition of influenza A virus (A/Perth/16/2009(H3N2)) neuraminidase using MUNANA substrate pre-incubated for 30 mins before substrate addition by f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus (strain A/USSR/90/1977 H1N1))
Freie Universitaet Berlin

Curated by ChEMBL
LigandPNGBDBM50056315(CHEBI:17558 | Quercitrin)
Affinity DataIC50: 1.09E+5nMAssay Description:Inhibition of influenza A virus (A/California/07/2009(H1N1)) pdm09 neuraminidase using MUNANA substrate pre-incubated for 30 mins before substrate ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50056315(CHEBI:17558 | Quercitrin)
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of PTP1B (unknown origin) using pNPP substrate measured after 3 mins by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2016
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
University of Pretoria

Curated by ChEMBL
LigandPNGBDBM50056315(CHEBI:17558 | Quercitrin)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate pretreated for 5 mins followed by substrate addition measured over 30 mins by spectro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2020
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
University of Pretoria

Curated by ChEMBL
LigandPNGBDBM50056315(CHEBI:17558 | Quercitrin)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Korea Institute of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50056315(CHEBI:17558 | Quercitrin)
Affinity DataIC50: 1.67E+5nMAssay Description:Inhibition of HIV1 recombinant integrase expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetGenome polyprotein(Dengue virus)
Queensland University of Technology

Curated by ChEMBL
LigandPNGBDBM50056315(CHEBI:17558 | Quercitrin)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of dengue virus NS5 RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50056315(CHEBI:17558 | Quercitrin)
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of sEH (unknown origin) assessed as reduction in 6-methoxy-2-naphthaldehyde formation using PHOME as substrate measured after 40 mins by f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
LigandPNGBDBM50056315(CHEBI:17558 | Quercitrin)
Affinity DataIC50: 6.31E+4nMAssay Description:Inhibition of human OATP2B1 expressed in Flp-In-CHO cells assessed as inhibition of OATP2B1 mediated DBF uptake using DBF as fluorescent substrate in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetGenome polyprotein(Dengue virus)
Queensland University of Technology

Curated by ChEMBL
LigandPNGBDBM50056315(CHEBI:17558 | Quercitrin)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of DENV/NS5 RNA-dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Babu Banarasi Das Northern India Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50056315(CHEBI:17558 | Quercitrin)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of MAO-A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50056315(CHEBI:17558 | Quercitrin)
Affinity DataKi:  3.96E+4nMAssay Description:Non competitive inhibition of sEH (unknown origin) using varying levels of PHOME as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed