BDBM50108802 3,11-difluoro-6,8,13-trimethyl-8H-quino[4,3,2-kl]acridin-13-ium; methyl sulfate(RHPS4)::CHEMBL158083::RHPS4

SMILES Cc1cc2n(C)c3ccc(F)cc3c3[n+](C)c4ccc(F)cc4c(c1)c23

InChI Key InChIKey=FJUYVGXXNUNWDT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50108802   

TargetTelomerase reverse transcriptase(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50108802(3,11-difluoro-6,8,13-trimethyl-8H-quino[4,3,2-kl]a...)
Affinity DataIC50: 330nMAssay Description:Inhibition of telomerase activity using TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50108802(3,11-difluoro-6,8,13-trimethyl-8H-quino[4,3,2-kl]a...)
Affinity DataIC50: 330nMAssay Description:Inhibition of telomerase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTelomerase reverse transcriptase(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50108802(3,11-difluoro-6,8,13-trimethyl-8H-quino[4,3,2-kl]a...)
Affinity DataIC50: 3.31E+8nMAssay Description:Inhibition of Homo sapiens (human) telomerase assessed as formation of G-tetraplexes by gel mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article