BDBM50039082 6,7-Dimethoxy-3-thiophen-3-yl-quinoline::CHEMBL66643::RPR-101511

SMILES COc1cc2cc(cnc2cc1OC)-c1ccsc1

InChI Key InChIKey=KGGRQYJJHXVWSI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50039082   

TargetPlatelet-derived growth factor receptor alpha/beta(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50039082(6,7-Dimethoxy-3-thiophen-3-yl-quinoline | RPR-1015...)
Affinity DataIC50: 461nMAssay Description:Inhibition of Platelet-derived growth factor receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50039082(6,7-Dimethoxy-3-thiophen-3-yl-quinoline | RPR-1015...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human PDGF receptor phosphorylation; 0.01-0.02More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50039082(6,7-Dimethoxy-3-thiophen-3-yl-quinoline | RPR-1015...)
Affinity DataIC50: 2.00E+4nMAssay Description:Concentration required to inhibit phosphorylation of isolated human epidermal growth factor tyrosine kinase receptor by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50039082(6,7-Dimethoxy-3-thiophen-3-yl-quinoline | RPR-1015...)
Affinity DataIC50: 461nMAssay Description:Inhibition of Platelet-derived growth factor receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed