BDBM50088000 (+/-)-11-[2-(2-methoxyphenyl)acryloyl]-1-(4-methylphenyl)-(1R,8R,9S,13S)-11-azatetracyclo[6.5.2.02,7.09,13]pentadeca-2,4,6-triene-9-carboxylic acid (RPR130401)::(1R,8R,9S,13S)-11-[2-(2-methoxyphenyl)prop-2-enoyl]-1-(4-methylphenyl)-11-azatetracyclo[6.5.2.0^{2,7}.0^{9,13}]pentadeca-2,4,6-triene-9-carboxylic acid::CHEMBL446112::RPR-130401

SMILES COc1ccccc1C(=C)C(=O)N1C[C@@H]2[C@](C1)([C@@H]1CC[C@@]2(c2ccc(C)cc2)c2ccccc12)C(O)=O

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50088000   

TargetDimer of Protein farnesyltransferase subunit beta(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50088000((+/-)-11-[2-(2-methoxyphenyl)acryloyl]-1-(4-methyl...)
Affinity DataIC50: 8nMAssay Description:Inhibition of FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed