BDBM50019250 5-(2-Fluoro-phenyl)-1-methyl-1,3-dihydro-benzo[e][1,4]diazepin-2-one::CHEMBL13095::Ro-05-4520

SMILES CN1c2ccccc2C(=NCC1=O)c1ccccc1F

InChI Key InChIKey=YVTVBCWQHDDTGB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50019250   

TargetCholecystokinin receptor type A(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50019250(CHEMBL13095 | Ro-05-4520 | 5-(2-Fluoro-phenyl)-1-m...)
Affinity DataIC50: 4.20E+4nMAssay Description:Half-maximal inhibition of [125I]CCK-33 binding to cholecystokinin A receptor from rat pancreatic tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetCholecystokinin receptor type A/Gastrin/cholecystokinin type B receptor(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50019250(CHEMBL13095 | Ro-05-4520 | 5-(2-Fluoro-phenyl)-1-m...)
Affinity DataIC50: 1.00E+5nMAssay Description:Half-maximal inhibition of [125I]-CCK-8(+) binding to cholecystokinin receptor from guinea pig brain tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50019250(CHEMBL13095 | Ro-05-4520 | 5-(2-Fluoro-phenyl)-1-m...)
Affinity DataIC50: 1.00E+5nMAssay Description:Half-maximal inhibition of [125I]gastrin binding to guinea pig gastric glandsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Harvard University

Curated by ChEMBL
LigandPNGBDBM50019250(CHEMBL13095 | Ro-05-4520 | 5-(2-Fluoro-phenyl)-1-m...)
Affinity DataIC50: 7.14E+7nMAssay Description:Binding affinity of compound towards Benzodiazepine receptor in a competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed