BDBM2385 2-(cyclohexylsulfanyl)-6-[(2,6-dichlorophenyl)methyl]-5-methyl-3,4-dihydropyrimidin-4-one::S-DABO::thio-DABO 5ll

SMILES Cc1c(Cc2c(Cl)cccc2Cl)nc(SC2CCCCC2)[nH]c1=O

InChI Key InChIKey=HZWGTHFFPVMGKI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2385   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Sapienza University of Rome

LigandPNGBDBM2385(2-(cyclohexylsulfanyl)-6-[(2,6-dichlorophenyl)meth...)
Affinity DataIC50: 4.90E+3nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2004
Entry Details Article
PubMed