BDBM50423650 CHEMBL522758::SB-410220

SMILES CN(C)c1ccc(NC(=O)Nc2ccnc3c(F)ccc(F)c23)cc1

InChI Key InChIKey=AZFKSWSBVCFBCG-UHFFFAOYSA-N

Data  2 KI  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50423650   

TargetOrexin/Hypocretin receptor type 1(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50423650(SB-410220 | CHEMBL522758)
Affinity DataKd:  4.5nMAssay Description:Binding affinity to OX1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50423650(SB-410220 | CHEMBL522758)
Affinity DataKi:  8.70nMAssay Description:Binding affinity to orexin receptor 1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50423650(SB-410220 | CHEMBL522758)
Affinity DataKi:  503nMAssay Description:Binding affinity to orexin receptor 2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed