BDBM50506744 CHEBI:73038::Parecoxib::SC-69124

SMILES CCC(=O)NS(=O)(=O)c1ccc(cc1)-c1c(C)onc1-c1ccccc1

InChI Key InChIKey=TZRHLKRLEZJVIJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50506744   

TargetProstaglandin G/H synthase 2(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50506744(CHEBI:73038 | Parecoxib | SC-69124)
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human COX2 expressed in baculovirus infected Sf9 insect cells using arachidonic acid as substrate preincubated for 10 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetNuclear receptor subfamily 4 group A member 2(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50506744(CHEBI:73038 | Parecoxib | SC-69124)
Affinity DataIC50: 1.34E+4nMAssay Description:Inverse agonist activity at Gal4-fused Nurr1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed