BDBM50084679 2-[1-(2-Carboxy-2-hydroxy-ethylcarbamoyl)-2-phenyl-ethylamino]-4-phenyl-butyric acid(SCH39370)::CHEMBL113759::SCH-39370

SMILES O[C@@H](CNC(=O)[C@H](Cc1ccccc1)NC(CCc1ccccc1)C(O)=O)C(O)=O

InChI Key InChIKey=QAQRHURCJWHRJU-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50084679   

TargetNeprilysin(Rat)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50084679(SCH-39370 | 2-[1-(2-Carboxy-2-hydroxy-ethylcarbamo...)
Affinity DataIC50: 11nMAssay Description:Inhibitory activity against EndopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50084679(SCH-39370 | 2-[1-(2-Carboxy-2-hydroxy-ethylcarbamo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against angiotensin I converting enzyme (ACE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetNeprilysin(Rabbit)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50084679(SCH-39370 | 2-[1-(2-Carboxy-2-hydroxy-ethylcarbamo...)
Affinity DataKi:  11nMAssay Description:Tested for binding affinity against neutral endopeptidase (NEP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed