BDBM50041921 5-{4-[2-(3,4,5-Trimethoxy-phenyl)-ethyl]-phenyl}-2,3-dihydro-imidazo[2,1-a]isoquinoline::CHEMBL449395::SDZ-64-412

SMILES COc1cc(CCc2ccc(cc2)C2=Cc3ccccc3C3=NCCN23)cc(OC)c1OC

InChI Key InChIKey=FKRBSORUVOGNEK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50041921   

TargetPlatelet-activating factor receptor(Human)
Sandoz Research Institute

Curated by ChEMBL
LigandPNGBDBM50041921(SDZ-64-412 | 5-{4-[2-(3,4,5-Trimethoxy-phenyl)-eth...)
Affinity DataIC50: 60nMAssay Description:In vitro PAF antagonistic activity by determining [3H]PAF binding to the PAF-receptor of human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Human)
Sandoz Research Institute

Curated by ChEMBL
LigandPNGBDBM50041921(SDZ-64-412 | 5-{4-[2-(3,4,5-Trimethoxy-phenyl)-eth...)
Affinity DataIC50: 40nMAssay Description:In vitro inhibition of [3H]PAF receptor binding to washed human platelet membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article