BDBM50586589 SR-302

SMILES CS(=O)(=O)N1CCCC(C1)NC(=O)[C@H](CCC1CCCCC1)NC(=O)c1ccc(CNC(=O)c2cnc3ccccn23)cc1

InChI Key InChIKey=WGMNFJAFXXXRLZ-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50586589   

TargetDiscoidin domain-containing receptor 2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50586589(SR-302)
Affinity DataIC50: 18nMAssay Description:Inhibition of DDR2 (unknown origin) expressed in HEK293T cells using NanoBRET NanoGlo substrate incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetEpithelial discoidin domain-containing receptor 1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50586589(SR-302)
Affinity DataIC50: 23nMAssay Description:Inhibition of DDR1 (unknown origin) expressed in HEK293T cells using NanoBRET NanoGlo substrate incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50586589(SR-302)
Affinity DataIC50: 125nMAssay Description:Inhibition of p38alpha (unknown origin) expressed in HEK293T cells using NanoBRET NanoGlo substrate incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50586589(SR-302)
Affinity DataIC50: 196nMAssay Description:Inhibition of p38beta (unknown origin) expressed in HEK293T cells using NanoBRET NanoGlo substrate incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50586589(SR-302)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of RIPK2 (unknown origin) expressed in HEK293T cells using NanoBRET NanoGlo substrate incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-5(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50586589(SR-302)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of RPS6KA5 (unknown origin) expressed in HEK293T cells using NanoBRET NanoGlo substrate incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50586589(SR-302)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of ABL1 (unknown origin) expressed in HEK293T cells using NanoBRET NanoGlo substrate incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed