BDBM223295 Sm8::US20240002326, Compound Sm8

SMILES COc1cccc(CCCCCCc2ccccc2)c1C(O)=O

InChI Key InChIKey=VHNNPYCCQIFODV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 223295   

TargetTranscription factor SOX-18(Mouse)
The University of Queensland

LigandPNGBDBM223295(Sm8 | US20240002326, Compound Sm8)
Affinity DataIC50: 3.27E+5nMpH: 7.5 T: 2°CAssay Description:The DNA-binding competition assay was performed in 25 μL, in black 384-well plates, using either 30 mM HEPES (N-2-Hydroxyethylpiperazine-N'-2-Etha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2017
Entry Details Article
PubMed
TargetTranscription factor SOX-18(Human)
University of Queensland

US Patent
LigandPNGBDBM223295(Sm8 | US20240002326, Compound Sm8)
Affinity DataIC50: 3.27E+5nMAssay Description:Different concentration ranges were tested in the FP-based DNA binding competition assay (0.2-200 uM, 10-500 uM, 10 uM-3 mM), with DMSO concentration...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2024
Entry Details
Go to US Patent