BDBM789755 (4-(4-(1-Phenylpropyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl)methanol::TIA05-134::US20250353856, Compound 5j

SMILES CCC(c1ccccc1)c1ncnc2[nH]c(-c3ccc(CO)cc3)cc12

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 789755   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 789755BDBM789755(TIA05-134 | (4-(4-(1-Phenylpropyl)-7H-pyrrolo[2,3-...)
Affinity DataIC50: 29nMAssay Description:The compounds were supplied in a 10 mM DMSO solution, and enzymatic CSF1R inhibition potency was determined by Invitrogen (TermoFisher) using their Z...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/11/2026
Entry Details
US Patent