BDBM50005256 (+/-)1-Methyl-2-(3,4,5-trimethoxy-phenyl)-ethylamine::1-Methyl-2-(3,4,5-trimethoxy-phenyl)-ethylamine::CHEMBL30336::TMA

SMILES COc1cc(CC(C)N)cc(OC)c1OC

InChI Key InChIKey=WGTASENVNYJZBK-UHFFFAOYSA-N

Data  52 KI  1 Kd  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 55 hits for monomerid = 50005256   

Target5-hydroxytryptamine receptor 2C(Human)
University of Oklahoma

LigandPNGBDBM50005256(CHEMBL30336 | (+/-)1-Methyl-2-(3,4,5-trimethoxy-ph...)
Affinity DataEC50:  47.4nMAssay Description:Data from pone.0009019.s006.doc, supplement tables.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
University of Oklahoma

LigandPNGBDBM50005256(CHEMBL30336 | (+/-)1-Methyl-2-(3,4,5-trimethoxy-ph...)
Affinity DataEC50:  41.3nMAssay Description:Data from pone.0009019.s006.doc, supplement tables.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50005256(CHEMBL30336 | (+/-)1-Methyl-2-(3,4,5-trimethoxy-ph...)
Affinity DataKd:  2.51E+3nMAssay Description:Affinity against 5-hydroxytryptamine 2B receptor in the isolated rat stomach fundusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
University of Oklahoma

LigandPNGBDBM50005256(CHEMBL30336 | (+/-)1-Methyl-2-(3,4,5-trimethoxy-ph...)
Affinity DataKi:  57.9nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
University of Oklahoma

LigandPNGBDBM50005256(CHEMBL30336 | (+/-)1-Methyl-2-(3,4,5-trimethoxy-ph...)
Affinity DataKi:  87.7nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50005256(CHEMBL30336 | (+/-)1-Methyl-2-(3,4,5-trimethoxy-ph...)
Affinity DataKi:  187nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
University of Bath

Curated by PDSP Ki Database
LigandPNGBDBM50005256(CHEMBL30336 | (+/-)1-Methyl-2-(3,4,5-trimethoxy-ph...)
Affinity DataKi:  260nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2012
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Eli Lilly

Curated by PDSP Ki Database
LigandPNGBDBM50005256(CHEMBL30336 | (+/-)1-Methyl-2-(3,4,5-trimethoxy-ph...)
Affinity DataKi:  307nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor(Cape York rat)
R. J. Reynolds Tobacco

Curated by PDSP Ki Database
LigandPNGBDBM50005256(CHEMBL30336 | (+/-)1-Methyl-2-(3,4,5-trimethoxy-ph...)
Affinity DataKi:  375nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2011
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Eli Lilly

Curated by PDSP Ki Database
LigandPNGBDBM50005256(CHEMBL30336 | (+/-)1-Methyl-2-(3,4,5-trimethoxy-ph...)
Affinity DataKi:  477nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetSigma intracellular receptor 2(Human)
University of Oklahoma

LigandPNGBDBM50005256(CHEMBL30336 | (+/-)1-Methyl-2-(3,4,5-trimethoxy-ph...)
Affinity DataKi:  537nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Oklahoma

LigandPNGBDBM50005256(CHEMBL30336 | (+/-)1-Methyl-2-(3,4,5-trimethoxy-ph...)
Affinity DataKi:  537nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 7(Human)
University of Oklahoma

LigandPNGBDBM50005256(CHEMBL30336 | (+/-)1-Methyl-2-(3,4,5-trimethoxy-ph...)
Affinity DataKi:  749nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Oklahoma

LigandPNGBDBM50005256(CHEMBL30336 | (+/-)1-Methyl-2-(3,4,5-trimethoxy-ph...)
Affinity DataKi:  1.68E+3nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetAlpha-2A adrenergic receptor(Human)
University of Oklahoma

LigandPNGBDBM50005256(CHEMBL30336 | (+/-)1-Methyl-2-(3,4,5-trimethoxy-ph...)
Affinity DataKi:  2.07E+3nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
University of Oklahoma

LigandPNGBDBM50005256(CHEMBL30336 | (+/-)1-Methyl-2-(3,4,5-trimethoxy-ph...)
Affinity DataKi:  2.86E+3nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
University of Oklahoma

LigandPNGBDBM50005256(CHEMBL30336 | (+/-)1-Methyl-2-(3,4,5-trimethoxy-ph...)
Affinity DataKi:  3.04E+3nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1E(Human)
University of Oklahoma

LigandPNGBDBM50005256(CHEMBL30336 | (+/-)1-Methyl-2-(3,4,5-trimethoxy-ph...)
Affinity DataKi:  3.37E+3nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
University of Oklahoma

LigandPNGBDBM50005256(CHEMBL30336 | (+/-)1-Methyl-2-(3,4,5-trimethoxy-ph...)
Affinity DataKi:  4.60E+3nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetAlpha-2C adrenergic receptor(Human)
University of Oklahoma

LigandPNGBDBM50005256(CHEMBL30336 | (+/-)1-Methyl-2-(3,4,5-trimethoxy-ph...)
Affinity DataKi:  5.01E+3nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50005256(CHEMBL30336 | (+/-)1-Methyl-2-(3,4,5-trimethoxy-ph...)
Affinity DataKi:  5.71E+3nMAssay Description:Compound was tested for binding affinity towards 5-HT1C (5-HT1C) receptor from frontal cortical regions of male Sprague-Dawley rat homogenates, using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Oklahoma

LigandPNGBDBM50005256(CHEMBL30336 | (+/-)1-Methyl-2-(3,4,5-trimethoxy-ph...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetDelta-type opioid receptor(Human)
University of Oklahoma

LigandPNGBDBM50005256(CHEMBL30336 | (+/-)1-Methyl-2-(3,4,5-trimethoxy-ph...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
University of Oklahoma

LigandPNGBDBM50005256(CHEMBL30336 | (+/-)1-Methyl-2-(3,4,5-trimethoxy-ph...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
University of Oklahoma

LigandPNGBDBM50005256(CHEMBL30336 | (+/-)1-Methyl-2-(3,4,5-trimethoxy-ph...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
University of Oklahoma

LigandPNGBDBM50005256(CHEMBL30336 | (+/-)1-Methyl-2-(3,4,5-trimethoxy-ph...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
University of Oklahoma

LigandPNGBDBM50005256(CHEMBL30336 | (+/-)1-Methyl-2-(3,4,5-trimethoxy-ph...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetHistamine H1 receptor(Human)
University of Oklahoma

LigandPNGBDBM50005256(CHEMBL30336 | (+/-)1-Methyl-2-(3,4,5-trimethoxy-ph...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetHistamine H2 receptor(Human)
University of Oklahoma

LigandPNGBDBM50005256(CHEMBL30336 | (+/-)1-Methyl-2-(3,4,5-trimethoxy-ph...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetCannabinoid receptor 1(Human)
University of Oklahoma

LigandPNGBDBM50005256(CHEMBL30336 | (+/-)1-Methyl-2-(3,4,5-trimethoxy-ph...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetCarnitine O-palmitoyltransferase 2, mitochondrial(Human)
University of Oklahoma

LigandPNGBDBM50005256(CHEMBL30336 | (+/-)1-Methyl-2-(3,4,5-trimethoxy-ph...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 2A(Human)
University of Oklahoma

LigandPNGBDBM50005256(CHEMBL30336 | (+/-)1-Methyl-2-(3,4,5-trimethoxy-ph...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
University of Oklahoma

LigandPNGBDBM50005256(CHEMBL30336 | (+/-)1-Methyl-2-(3,4,5-trimethoxy-ph...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetHistamine H3 receptor(Human)
University of Oklahoma

LigandPNGBDBM50005256(CHEMBL30336 | (+/-)1-Methyl-2-(3,4,5-trimethoxy-ph...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetHistamine H4 receptor(Human)
University of Oklahoma

LigandPNGBDBM50005256(CHEMBL30336 | (+/-)1-Methyl-2-(3,4,5-trimethoxy-ph...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Human)
University of Oklahoma

LigandPNGBDBM50005256(CHEMBL30336 | (+/-)1-Methyl-2-(3,4,5-trimethoxy-ph...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Oklahoma

LigandPNGBDBM50005256(CHEMBL30336 | (+/-)1-Methyl-2-(3,4,5-trimethoxy-ph...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
University of Bath

Curated by PDSP Ki Database
LigandPNGBDBM50005256(CHEMBL30336 | (+/-)1-Methyl-2-(3,4,5-trimethoxy-ph...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2012
Entry Details
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of Oklahoma

LigandPNGBDBM50005256(CHEMBL30336 | (+/-)1-Methyl-2-(3,4,5-trimethoxy-ph...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
University of Oklahoma

LigandPNGBDBM50005256(CHEMBL30336 | (+/-)1-Methyl-2-(3,4,5-trimethoxy-ph...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Oklahoma

LigandPNGBDBM50005256(CHEMBL30336 | (+/-)1-Methyl-2-(3,4,5-trimethoxy-ph...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetD(1B) dopamine receptor(Human)
University of Oklahoma

LigandPNGBDBM50005256(CHEMBL30336 | (+/-)1-Methyl-2-(3,4,5-trimethoxy-ph...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetAlpha-1A adrenergic receptor(Human)
University of Oklahoma

LigandPNGBDBM50005256(CHEMBL30336 | (+/-)1-Methyl-2-(3,4,5-trimethoxy-ph...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetAlpha-1B adrenergic receptor(Human)
University of Oklahoma

LigandPNGBDBM50005256(CHEMBL30336 | (+/-)1-Methyl-2-(3,4,5-trimethoxy-ph...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetD(1A) dopamine receptor(Human)
University of Oklahoma

LigandPNGBDBM50005256(CHEMBL30336 | (+/-)1-Methyl-2-(3,4,5-trimethoxy-ph...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetAlpha-2B adrenergic receptor(Human)
University of Oklahoma

LigandPNGBDBM50005256(CHEMBL30336 | (+/-)1-Methyl-2-(3,4,5-trimethoxy-ph...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 6(Human)
University of Oklahoma

LigandPNGBDBM50005256(CHEMBL30336 | (+/-)1-Methyl-2-(3,4,5-trimethoxy-ph...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetBeta-1 adrenergic receptor(Human)
University of Oklahoma

LigandPNGBDBM50005256(CHEMBL30336 | (+/-)1-Methyl-2-(3,4,5-trimethoxy-ph...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetBeta-2 adrenergic receptor(Human)
University of Oklahoma

LigandPNGBDBM50005256(CHEMBL30336 | (+/-)1-Methyl-2-(3,4,5-trimethoxy-ph...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Human)
University of Oklahoma

LigandPNGBDBM50005256(CHEMBL30336 | (+/-)1-Methyl-2-(3,4,5-trimethoxy-ph...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
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