BDBM50242177 5,8-dihydroxy-10-methoxy-2-methyl-4H-benzo[h]chromen-4-one::5,8-dihydroxy-10-methoxy-2-propyl-4H-benzo[h]chromen-4-one::CHEMBL454794::TMC-256C1

SMILES COc1cc(O)cc2cc(O)c3c(oc(C)cc3=O)c12

InChI Key InChIKey=LMPLCDBTXJVFFT-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50242177   

TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Nci-Frederick

Curated by ChEMBL

LigandBDBM50242177(TMC-256C1 | 5,8-dihydroxy-10-methoxy-2-methyl-4H-b...)Copy SMILESCopy InChI

Affinity DataIC50: 1.28E+4nMAssay Description:Inhibition of ABCG2-mediated drug efflux expressed in human NCI-H460 cellsMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
12/31/2012
Entry Details Article
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