BDBM50233945 CHEBI:18344::Kynurenic Acid::TRANSTORINE

SMILES OC(=O)c1cc(=O)c2ccccc2[nH]1

InChI Key InChIKey=HCZHHEIFKROPDY-UHFFFAOYSA-N

Data  1 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50233945   

TargetG-protein coupled receptor 35(Human)
University of North Carolina At Greensboro

Curated by ChEMBL
LigandPNGBDBM50233945(TRANSTORINE | CHEBI:18344 | Kynurenic Acid)
Affinity DataIC50: 3.90E+4nMAssay Description:Antagonist activity at GPR35 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2019
Entry Details Article
PubMed
TargetG-protein coupled receptor 35(Human)
University of North Carolina At Greensboro

Curated by ChEMBL
LigandPNGBDBM50233945(TRANSTORINE | CHEBI:18344 | Kynurenic Acid)
Affinity DataEC50:  1.52E+5nMAssay Description:Agonist activity at human GPR35 expressed in CHO-K1 cells by DMR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
TargetG-protein coupled receptor 35(Human)
University of North Carolina At Greensboro

Curated by ChEMBL
LigandPNGBDBM50233945(TRANSTORINE | CHEBI:18344 | Kynurenic Acid)
Affinity DataEC50:  2.17E+5nMAssay Description:Agonist activity at human GPR35 expressed in CHO-K1 cells after 90 mins by beta-arrestin 2 recruitment assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
TargetG-protein coupled receptor 35(Human)
University of North Carolina At Greensboro

Curated by ChEMBL
LigandPNGBDBM50233945(TRANSTORINE | CHEBI:18344 | Kynurenic Acid)
Affinity DataEC50:  2.17E+5nMAssay Description:Agonist activity at human GPR35 receptor by beta-arrestin assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetG-protein coupled receptor 35(Human)
University of North Carolina At Greensboro

Curated by ChEMBL
LigandPNGBDBM50233945(TRANSTORINE | CHEBI:18344 | Kynurenic Acid)
Affinity DataEC50:  1.52E+5nMAssay Description:Agonist activity at human GPR35 receptor by DMR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed