BDBM50328705 CHEMBL1270156::Tanogitran

SMILES Cn1c(CNc2ccc(cc2)C(N)=N)nc2cc(ccc12)[C@@](C)(NCC(O)=O)C(=O)N1CCCC1

InChI Key InChIKey=MAOALPSHCIBFJZ-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50328705   

TargetCoagulation factor X(Human)
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50328705(Tanogitran | CHEMBL1270156)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of factor-10a (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetProthrombin(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50328705(Tanogitran | CHEMBL1270156)
Affinity DataKi:  2.70nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50328705(Tanogitran | CHEMBL1270156)
Affinity DataKi:  26nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed