BDBM50216795 (3R)-6-cyclohexyl-N-hydroxy-3-(1,2,4-oxadiazol-5-yl)hexanamide::(R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-yl)-1,2,4-oxadiazole-3-carboxamide::CHEMBL226630::UK-383367

SMILES NC(=O)c1noc(n1)[C@H](CCCC1CCCCC1)CC(=O)NO

InChI Key InChIKey=ARJCBSRIPGJMAD-UHFFFAOYSA-N

Data  17 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50216795   

TargetBone morphogenetic protein 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216795((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50: 44nMAssay Description:Inhibition of human procollagen C-proteinase expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216795((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human MMP3 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216795((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of interstitial MMP1 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50216795((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50: 900nMAssay Description:Inhibition of PDE4DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50216795((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of PDE4CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50216795((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of PDE4BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50216795((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of PDE4AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216795((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of human MMP2 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBone morphogenetic protein 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216795((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50: 44nMAssay Description:Inhibition of human procollagen C-proteinase assessed as [3H]procollagen turnover by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216795((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human MMP9 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216795((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216795((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216795((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216795((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216795((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBone morphogenetic protein 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216795((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50: 26nMAssay Description:Inhibition of human procollagen C-proteinase assessed as [3H]procollagen turnover by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216795((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human MMP14 catalytic domain by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed