BDBM50127004 CHEMBL2062868::Vernolide-B

SMILES CO[C@@]12CC[C@@](C)(O1)\C=C1\OC(=O)C(COC(C)=O)=C1[C@H](C[C@H]2C)OC(=O)C(\C)=C\C

InChI Key InChIKey=CIBBPLMBWXKCDP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50127004   

TargetSignal transducer and activator of transcription 3(Human)
University of Hawaii At Hilo

Curated by ChEMBL
LigandPNGBDBM50127004(Vernolide-B | CHEMBL2062868)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of Stat3 dimer DNA binding activity in human U251MG cells nuclear extract after 1.5 hrs by EMSA using radiolabeled probe hSIEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
University of Hawaii At Hilo

Curated by ChEMBL
LigandPNGBDBM50127004(Vernolide-B | CHEMBL2062868)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of Stat3 dimer DNA binding activity in human U373MG cells nuclear extract after 1.5 hrs by EMSA using radiolabeled probe hSIEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed