BDBM50366564 CHEMBL1790051::CHEMBL83729::WIN-35065-2
SMILES COC(=O)[C@@H]1C2CC[C@H](C[C@@H]1c1ccccc1)N2C
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 104 hits for monomerid = 50366564
Affinity DataIC50: 21nMAssay Description:Inhibition of [3H]citalopram binding to the serotonin transporter (5-HT) in monkey caudate-putamen.More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of [3H]citalopram binding to the serotonin transporter (5-HT) in monkey caudate-putamen.More data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Competitive inhibition against [3H]cocaine binding to cocaine receptor in bovine striatal tissueMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of [3H]cocaine binding to the dopamine transporter.More data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Competitive inhibition against [3H]cocaine binding to cocaine receptor in bovine striatal tissueMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of [3H]cocaine binding to the dopamine transporter.More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:50% Inhibition against dopamine transporter (DAT) in rat striatal tissue by displacing [3H]WIN-35428 radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Potency for the inhibition of [3H]WIN-35428 binding to the dopamine transporterMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibitory activity against radioligand [3H]WIN-35428 binding at the dopamine transporterMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Binding affinity towards Dopamine transporter by displacement of [3H]WIN-35428 radioligand from rat brainMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Displacement of [3H]WIN-35428 from DATMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Displacement of [3H]WIN-35428 from human DATMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine (DA) transporterMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Displacement of [3H]WIN-35428 from DATMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Binding affinity at the Dopamine transporter in rat striata by inhibition of 0.5 nM [3H]WIN-35428 bindingMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Potency for the inhibition of [3H]WIN-35428 binding to the dopamine transporterMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of [3H]WIN-35428 binding to the cocaine binding site on the dopamine transporter (DAT) in synaptosomal membrane preparations from rat stri...More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibitory activity against Dopamine transporter using 0.5 nM [3H]WIN-35428 as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Compound was evaluated for the inhibition of [3H]WIN-35428l binding to dopamine transporterMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of [3H]WIN-35428 binding to the cocaine binding site on the dopamine transporter (DAT) in synaptosomal membrane preparations from rat stri...More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of [3H]WIN-35428 binding at dopamine transporter was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibitory concentration required to inhibit dopamine transporter DAT was determined by using [3H]WIN-35428 radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Concentration required to inhibit 50% of radioligand binding ([3H]WIN-35428) to the dopamine (DA) transporter in ratMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:In vitro inhibitory activity against radioligand [3H]-WN 35,428 binding to dopamine transporter (DAT) in rat striatal tissueMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Displacement of [3H]WIN-35428 from DATMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Affinity against cocaine binding site of dopamine transporter in rat striatum using [3H]2b as radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Binding affinity against dopamine transporter in rat caudate putamen tissue using [3H]WIN-35428 radioligand. (from other reference)More data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Binding affinity towards dopamine transporter using [3H]WIN-35428 as radioligand from rat caudate putamen tissue (high affinity)More data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Binding affinity against dopamine transporter in rat caudate putamen tissue using [3H]WIN-35428 radioligand. (from other reference)More data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Binding affinity towards dopamine transporter using [3H]WIN-35428 as radioligand in rat caudate-putamen tissueMore data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Displacement of [3H]WIN-35428 from dopamine transporter in rat caudate putamen tissueMore data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Binding affinity was determined against cocaine binding site by measuring the ability of compound to displace bound [3H]dopamine from rat caudate-put...More data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Binding affinity towards dopamine transporter using [3H]WIN-35428 as radioligand in rat caudate-putamen tissueMore data for this Ligand-Target Pair
Affinity DataKi: 37nMAssay Description:Inhibition of [3H]NE uptake by rat frontal cortex Norepinephrine transporterMore data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Inhibition of [3H]cocaine binding to the dopamine transporter.More data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Inhibition of [3H]DA uptake by rat striatal dopamine transporterMore data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Inhibition of high affinity uptake of [3H]dopamine into nerve endings (synaptosomes) prepared from various regions of the rat brain.More data for this Ligand-Target Pair
Affinity DataKi: 55nMAssay Description:Tested for the binding affinity towards Norepinephrine transporter in rat cerebral cortex by displacing [3H]nisoxetine radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 65nMAssay Description:Inhibition of [3H]3-beta-(4-fluorophenyl)tropane-2beta-carboxylic acid methyl ester binding to dopamine transporter of cynomolgus monkey striatumMore data for this Ligand-Target Pair
Affinity DataIC50: 65nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putamenMore data for this Ligand-Target Pair
Affinity DataKi: 87nMAssay Description:Binding affinity to dopamine transporter (DAT) using [3H]WIN-35428 as a radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 89nMAssay Description:Inhibition of [3H]mazindol binding to dopamine transporter of rat striatal membranes.More data for this Ligand-Target Pair
Affinity DataIC50: 101nMAssay Description:inhibition of [3H]WIN-35428 binding to the dopamine transporter (DAT) in monkey caudate-putamen.More data for this Ligand-Target Pair
Affinity DataIC50: 101nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporterMore data for this Ligand-Target Pair
Affinity DataIC50: 101nMAssay Description:inhibition of [3H]WIN-35428 binding to the dopamine transporter (DAT) in monkey caudate-putamen.More data for this Ligand-Target Pair
Affinity DataIC50: 101nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporterMore data for this Ligand-Target Pair
Affinity DataIC50: 119nMAssay Description:Inhibition of [3H]mazindol binding to the dopamine transporter.More data for this Ligand-Target Pair
Affinity DataKi: 173nMAssay Description:Ratio of Ki value towards Serotonin transporter to that of dopamine transporterMore data for this Ligand-Target Pair
Affinity DataKi: 178nMAssay Description:Inhibition of [3H]paroxetine binding at serotonin transporter was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 178nMAssay Description:Displacement of [3H]paroxetine from 5HTTMore data for this Ligand-Target Pair