BDBM50006822 1,1-Diethyl-3-{2-hydroxy-2-[3-(quinolin-2-ylmethoxy)-phenyl]-ethyl}-3-methyl-urea::CHEMBL417968::WY-47120

SMILES CCN(CC)C(=O)N(C)C[C@H](O)c1cccc(OCc2ccc3ccccc3n2)c1

InChI Key InChIKey=TYIBMMJUKQOSPL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50006822   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Wyeth Laboratories

Curated by ChEMBL
LigandPNGBDBM50006822(CHEMBL417968 | WY-47120 | 1,1-Diethyl-3-{2-hydroxy...)
Affinity DataIC50: 2.40E+3nMAssay Description:Ability to inhibit 5-lipoxygenase in guinea pigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50006822(CHEMBL417968 | WY-47120 | 1,1-Diethyl-3-{2-hydroxy...)
Affinity DataIC50: 2.00E+3nMAssay Description:The compound was tested for inhibitory activity against 5-Lipoxygenase receptor in rat polymorphonuclear leukocytes[PMNS]More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth Laboratories

Curated by ChEMBL
LigandPNGBDBM50006822(CHEMBL417968 | WY-47120 | 1,1-Diethyl-3-{2-hydroxy...)
Affinity DataIC50: 1.00E+5nMAssay Description:Ability to inhibit Prostaglandin G/H synthase in guinea pigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed